Mechanism of Blood Clotting

The figure below shows the mechanism of blood clotting.


  1. When a blood vessel is damaged, platelets will gather around the wound and coagulate.
  2. At the same time, an enzyme called thrombokinase will be released.
  3. Thrombokinase will convert the inactive prothrombin to the active thrombin.
  4. The thrombin will then catalyses the soluble fibrinogen to the insoluble fibrin.
  5. Fibrin will form a fibrous network to trap the blood cells and form the blood clot.